HSP90 ORCHESTRATES TRANSCRIPTIONAL REGULATION BY HSF1 AND CELL WALL REMODELLING BY MAPK SIGNALLING DURING THERMAL ADAPTATION IN A PATHOGENIC YEAST.

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.

Thermal adaptation is essential in all organisms.In yeasts, the heat shock response is commanded by the heat shock transcription factor Hsf1.Here we have integrated unbiased genetic screens with directed molecular dissection to demonstrate that multiple signalling cascades contribute to thermal adaptation in the pathogenic yeast Candida albicans.We

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Protective Effects of Wheat Grass on Histopathology of Some Organs and Biomarkers Parameters Against Lead Acetate Toxicity in Wistar Rats

This study focuses on the search for a natural treatment to reduce lead toxicity in male Wistar rat by using the aquous extract of wheatgrass Triticum aestivum (WG).In addition to the control group (C), rats were exposed to a diet containing 600 mg Pb acetate/Kg diet (Pb), or combined with the WG at 9g/100g diet (Pb-WG) for a best 6.7 powerstroke i

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Comparative genome sequencing and analyses of Mycobacterium cosmeticum reveal potential for biodesulfization of gasoline.

Mycobacterium cosmeticum is a nontuberculous Mycobacterium recovered from different water sources including household potable water and water collected at nail salon.Individual cases of this bacterium have been reported to be associated with gastrointestinal tract infections.Here we present the first whole-genome study and comparative analysis of t

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